Peter MacCallum Cancer Centre
Melbourne, Australia
Prof Jeanne Tie is the lower gastrointestinal medical oncology and trials lead at the Peter MacCallum Cancer Centre, and senior research fellow at the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Her research focusses on personalising treatment for patients with colorectal cancer with prognostic and predictive biomarkers, in particular the clinical applications of circulating tumor DNA (ctDNA). A critical impact of her research program is demonstrating that ctDNA detection after surgical removal of early-stage colorectal cancer is a highly accurate marker of molecular residual disease (MRD) and subsequent recurrence, and importantly, can be used to identify those at risk of recurrence for additional chemotherapy after surgery. She leads several ctDNA-based randomized clinical trials in colorectal cancer which aim to assess the clinical utility of ctDNA as a minimal residual disease marker to guide adjuvant treatment decision, including the DYNAMIC study which was published in the New England Journal of Medicine (June 2022). Her research was recognised by national and international awards/prizes such as the ASCO Bradley Stuart Beller Merit Award, ASCO Cancer Foundation Young Investigator’s Award and the AACR Team Science Award (The International Liquid Biopsy Initiative Team). She has published extensively in the field of colorectal cancer and serves as the chair on the AGITG (Australasian Gastrointestinal Trials Group) Lower GI working party, member of AGITG’s Scientific Advisory Committee and Research Operation Committee, ESMO Colorectal Tumour Faculty, and the Cancer Adjudication Committee for the ASPREE (Aspirin in Reducing Events in the Elderly) International study.
Debate: Are We Ready to Integrate ctDNA in Treatment Selection - YES
Friday, June 30, 2023
15:40 – 15:50 CEST
Debate: Are We Ready to Integrate ctDNA in Treatment Selection - DISCUSSION
Friday, June 30, 2023
16:00 – 16:10 CEST